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CBD and Epilepsy


Are you a victim of epilepsy and seizures? Do you know somebody who has been a victim of this misfortune for long time? Then the article bellow is going to enable you to help yourself or the people you love.

Epilepsy is a disorder of the central nervous system described by loss of consciousness and convulsions. Epilepsy is an extreme neurological disorder that can result in unpredictable seizures and a variety of other health conditions. The seizures caused by epilepsy are because of issues of electrical imbalance of brain. Roughly 1 of each 26 Americans will have a seizure issue sooner or later in life. Estimates indicate roughly three million Americans have epilepsy at the present time. Every year, another 200,000 people receive an epilepsy diagnosis. This disorder produces extreme and abnormal electrical movement in the brain, which can cause seizures. This disorder can be caused by brain damage, a tumor or a brain infection, however as a rule, the exact reason is unknown. Metabolic disturbances also can influence the disorder in some cases.

Epileptic Seizures vary altogether by the way they show physically, the time they last and how extreme they are. Seizures can be categorized as one of two classes: focal or generalized and Complex.

Simple seizures happen when irregular electrical discharges, or misfiring occurs in just a single portion of the brain. Patients stay conscious during seizures, and they experience no debilitation to memory and they may feel jerking, temporary paralysis, changes in vision, difficulty making simple movements or changes in mood etc. This kind of seizure affects almost 15 percent of epileptic people.

Complex seizures result in unconsciousness with memory loss. A few people perform abnormal movement during the seizure like walking in circles or rubbing their hands together. A complex seizure may make the patient watch stupified or out of it. Complex seizures affects more than half of people with epilepsy.

The reactions of epilepsy can be devastating upon the type and the condition. While some may have intermittent seizures, others may totally be immersed in the condition that hold on in a semi- vegetative state. Some of the effects of epilepsy can be described by the following:

Social impact: not doing well in social environments such as school and work
Learning disabilities
Cognitive disabilities
Behavioral changes, anxiety and mood variance
Unexplained injuries from seizure (falls, stiffness, illnesses)
Osteoporosis
Reproductive health deterioration
Risk of death


At present, different medicines are available depending on types of epileptic disorder. Frequently, these prescriptions come with unbearable side effects or sometime putting the patient in a vegetative state. In this circumstances where no medicine seems to be efficient, guardians are frequently left pondering what there is to do. For those, the effects of cannabis especially CBD on epilepsy have been under discussion for a number of years.

Ancient Chinese and Persian medical texts — and modern anecdotes — suggest that cannabis is useful for treating seizures. Cannabis and its subsidiaries have been documented to being anti-epileptic since 1881. Today, the guarantee of cannabidiol (CBD) as an anti-epileptic treatment is prompting people to move on from regular treatments to CBD.

What is Cannabidiol or CBD
Cannabidiol—CBD—is a cannabis compound that has remarkable medical and recreational benefits, but does not make people feel “High”. It can actually prevent the psychoactivity of THC. Cannabidiol is one of at least 113 active cannabinoids identified in cannabis. It is a major phytocannabinoid, accounting for up to 40% of the plant's extract. The fact is that CBD-infused cannabis strains are non-psychoactive or less psychoactive than THC-dominant strains. It’s make CBD products a good option for patients looking for relief from inflammation, pain, anxiety, psychosis, seizures, spasms, and other conditions without disconcerting feelings of lethargy or dysphoria.

Medical researchers have confirmed what some desperate parents have been claiming for quite a long time—that cannabidiol (CBD) can decrease epileptic seizures in a gentle manner.

CBD oil is currently being researched as a conceivable cure for epilepsy. When it has entered your blood circulatory system, CBD oil works by interacting with particular brain neuron receptors: opioid, which helps in pain relief during seizures, dopamine receptors that manage psychological and behavioral issues, and serotonin receptors, which are in charge of physical and emotional issues during an epileptic seizures.


An international group of scientists including University of Melbourne Chair of Pediatric Neurology and Austin Health Director of Pediatrics, Professor Ingrid Scheffer, considered cannabidiol for the treatment of seizures. The outcomes are published in The New England Journal of Medicine stated that cannabidiol (CBD) as an effective anti-seizure drug for epileptic disorder.

This study shows that, cannabinoids can decrease seizures via the activation of the brain’s CB1 receptors, which are found in the memory-related areas of the brain and within the nervous system.

There was a recent study that was conducted at the Virginia Commonwealth University that proved that the cannabinoids from cannabis give benefits that aren't regularly found in traditional pharmaceutical medications in epilepsy treatment.

A recent study published in the US National Library of Medicine said that, Cannabinoids are potentially beneficial to those suffering from neurological disorders, such as epilepsy.

A study at Children’s Hospital Colorado reviewed cases of pediatric patients suffering from epilepsy who received treatment using a cannabis extract. Of those patients, 57 percent saw some reduction in seizure activity. Thirty-three percent of those patients had their seizure activity reduced by 50 percent or more.

Interestingly, the US government, through the Department of Health and Human Services (HHS), holds a patent on cannabis, specifically on cannabidiol (CBD) as a neuroprotectant and an antioxidant and it is also approved by the DEA and FDA.

Closing Word

Patients who are suffering from epilepsy may pick up a huge advantage from the use of our full spectrum CBD products to prevent and decrease the misfortune of seizures. Those who are concerned about the psychoactive impacts of THC, CBD is the best option for them. If a friend or family member of you is epileptic and is thinking about cannabis to help with the seizures, then nothing to worry about, just visit our website and pick your perfect CBD product.


Keywords: Cannabidiol, CBD, Full Spectrum, Organic, Non-GMO, Seizures.

References:

Cannabis, cannabidiol, and epilepsy--from receptors to clinical response.
Szaflarski JP1, Bebin EM2.
https://www.ncbi.nlm.nih.gov/pubmed/25282526



Nonpsychotropic Plant Cannabinoids, Cannabidivarin (CBDV) and Cannabidiol (CBD), Activate and Desensitize Transient Receptor Potential Vanilloid 1 (TRPV1) Channels in Vitro: Potential for the Treatment of Neuronal Hyperexcitability
Fabio Arturo Iannotti†, Charlotte L. Hill‡, Antonio Leo‡§, Ahlam Alhusaini‡, Camille Soubrane‡, Enrico Mazzarella†, Emilio Russo∥, Benjamin J. Whalley‡, Vincenzo Di Marzo*†, and Gary J. Stephens
https://pubs.acs.org/doi/pdf/10.1021/cn5000524



Chronic administration of cannabidiol to healthy volunteers and epileptic patients.
Cunha JM, Carlini EA, Pereira AE, Ramos OL, Pimentel C, Gagliardi R, Sanvito WL, Lander N, Mechoulam R.
https://www.ncbi.nlm.nih.gov/pubmed/7413719

Cannabidiol: promise and pitfalls.
Welty TE1, Luebke A2, Gidal BE3.
https://www.ncbi.nlm.nih.gov/pubmed/25346628



Cannabidivarin(CBDV)suppresses pentylenetetrazole(PTZ)-induced increasesinepilepsy-relatedgene expression
Naoki Amada1,2,3, Yuki Yamasaki1,2,3, Claire M. Williams2 and Benjamin J. Whalley1
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840466/pdf/peerj-01-214.pdf


Report from a Survey of Parents Regarding the Use of Cannabidiol (Medicinal cannabis) in Mexican Children with Refractory Epilepsy.
Aguirre-Velázquez CG1.
https://www.ncbi.nlm.nih.gov/pubmed/28392943



Cannabidiol Treatment for Refractory Seizures in Sturge-Weber Syndrome.
Kaplan EH1, Offermann EA1, Sievers JW2, Comi AM3.
https://www.ncbi.nlm.nih.gov/pubmed/28454984


Could Cannabidiol be a Treatment Option for Intractable Childhood and Adolescent Epilepsy?
Koo CM1, Kang HC2.

Hypnotic and antiepileptic effects of cannabidiol.
Carlini EA, Cunha JM.
https://www.ncbi.nlm.nih.gov/pubmed/7028792









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