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CBD and Epilepsy


Are you a victim of epilepsy and seizures? Do you know somebody who has been a victim of this misfortune for long time? Then the article bellow is going to enable you to help yourself or the people you love.

Epilepsy is a disorder of the central nervous system described by loss of consciousness and convulsions. Epilepsy is an extreme neurological disorder that can result in unpredictable seizures and a variety of other health conditions. The seizures caused by epilepsy are because of issues of electrical imbalance of brain. Roughly 1 of each 26 Americans will have a seizure issue sooner or later in life. Estimates indicate roughly three million Americans have epilepsy at the present time. Every year, another 200,000 people receive an epilepsy diagnosis. This disorder produces extreme and abnormal electrical movement in the brain, which can cause seizures. This disorder can be caused by brain damage, a tumor or a brain infection, however as a rule, the exact reason is unknown. Metabolic disturbances also can influence the disorder in some cases.

Epileptic Seizures vary altogether by the way they show physically, the time they last and how extreme they are. Seizures can be categorized as one of two classes: focal or generalized and Complex.

Simple seizures happen when irregular electrical discharges, or misfiring occurs in just a single portion of the brain. Patients stay conscious during seizures, and they experience no debilitation to memory and they may feel jerking, temporary paralysis, changes in vision, difficulty making simple movements or changes in mood etc. This kind of seizure affects almost 15 percent of epileptic people.

Complex seizures result in unconsciousness with memory loss. A few people perform abnormal movement during the seizure like walking in circles or rubbing their hands together. A complex seizure may make the patient watch stupified or out of it. Complex seizures affects more than half of people with epilepsy.

The reactions of epilepsy can be devastating upon the type and the condition. While some may have intermittent seizures, others may totally be immersed in the condition that hold on in a semi- vegetative state. Some of the effects of epilepsy can be described by the following:

Social impact: not doing well in social environments such as school and work
Learning disabilities
Cognitive disabilities
Behavioral changes, anxiety and mood variance
Unexplained injuries from seizure (falls, stiffness, illnesses)
Osteoporosis
Reproductive health deterioration
Risk of death


At present, different medicines are available depending on types of epileptic disorder. Frequently, these prescriptions come with unbearable side effects or sometime putting the patient in a vegetative state. In this circumstances where no medicine seems to be efficient, guardians are frequently left pondering what there is to do. For those, the effects of cannabis especially CBD on epilepsy have been under discussion for a number of years.

Ancient Chinese and Persian medical texts — and modern anecdotes — suggest that cannabis is useful for treating seizures. Cannabis and its subsidiaries have been documented to being anti-epileptic since 1881. Today, the guarantee of cannabidiol (CBD) as an anti-epileptic treatment is prompting people to move on from regular treatments to CBD.

What is Cannabidiol or CBD
Cannabidiol—CBD—is a cannabis compound that has remarkable medical and recreational benefits, but does not make people feel “High”. It can actually prevent the psychoactivity of THC. Cannabidiol is one of at least 113 active cannabinoids identified in cannabis. It is a major phytocannabinoid, accounting for up to 40% of the plant's extract. The fact is that CBD-infused cannabis strains are non-psychoactive or less psychoactive than THC-dominant strains. It’s make CBD products a good option for patients looking for relief from inflammation, pain, anxiety, psychosis, seizures, spasms, and other conditions without disconcerting feelings of lethargy or dysphoria.

Medical researchers have confirmed what some desperate parents have been claiming for quite a long time—that cannabidiol (CBD) can decrease epileptic seizures in a gentle manner.

CBD oil is currently being researched as a conceivable cure for epilepsy. When it has entered your blood circulatory system, CBD oil works by interacting with particular brain neuron receptors: opioid, which helps in pain relief during seizures, dopamine receptors that manage psychological and behavioral issues, and serotonin receptors, which are in charge of physical and emotional issues during an epileptic seizures.


An international group of scientists including University of Melbourne Chair of Pediatric Neurology and Austin Health Director of Pediatrics, Professor Ingrid Scheffer, considered cannabidiol for the treatment of seizures. The outcomes are published in The New England Journal of Medicine stated that cannabidiol (CBD) as an effective anti-seizure drug for epileptic disorder.

This study shows that, cannabinoids can decrease seizures via the activation of the brain’s CB1 receptors, which are found in the memory-related areas of the brain and within the nervous system.

There was a recent study that was conducted at the Virginia Commonwealth University that proved that the cannabinoids from cannabis give benefits that aren't regularly found in traditional pharmaceutical medications in epilepsy treatment.

A recent study published in the US National Library of Medicine said that, Cannabinoids are potentially beneficial to those suffering from neurological disorders, such as epilepsy.

A study at Children’s Hospital Colorado reviewed cases of pediatric patients suffering from epilepsy who received treatment using a cannabis extract. Of those patients, 57 percent saw some reduction in seizure activity. Thirty-three percent of those patients had their seizure activity reduced by 50 percent or more.

Interestingly, the US government, through the Department of Health and Human Services (HHS), holds a patent on cannabis, specifically on cannabidiol (CBD) as a neuroprotectant and an antioxidant and it is also approved by the DEA and FDA.

Closing Word

Patients who are suffering from epilepsy may pick up a huge advantage from the use of our full spectrum CBD products to prevent and decrease the misfortune of seizures. Those who are concerned about the psychoactive impacts of THC, CBD is the best option for them. If a friend or family member of you is epileptic and is thinking about cannabis to help with the seizures, then nothing to worry about, just visit our website and pick your perfect CBD product.


Keywords: Cannabidiol, CBD, Full Spectrum, Organic, Non-GMO, Seizures.

References:

Cannabis, cannabidiol, and epilepsy--from receptors to clinical response.
Szaflarski JP1, Bebin EM2.
https://www.ncbi.nlm.nih.gov/pubmed/25282526



Nonpsychotropic Plant Cannabinoids, Cannabidivarin (CBDV) and Cannabidiol (CBD), Activate and Desensitize Transient Receptor Potential Vanilloid 1 (TRPV1) Channels in Vitro: Potential for the Treatment of Neuronal Hyperexcitability
Fabio Arturo Iannotti†, Charlotte L. Hill‡, Antonio Leo‡§, Ahlam Alhusaini‡, Camille Soubrane‡, Enrico Mazzarella†, Emilio Russo∥, Benjamin J. Whalley‡, Vincenzo Di Marzo*†, and Gary J. Stephens
https://pubs.acs.org/doi/pdf/10.1021/cn5000524



Chronic administration of cannabidiol to healthy volunteers and epileptic patients.
Cunha JM, Carlini EA, Pereira AE, Ramos OL, Pimentel C, Gagliardi R, Sanvito WL, Lander N, Mechoulam R.
https://www.ncbi.nlm.nih.gov/pubmed/7413719

Cannabidiol: promise and pitfalls.
Welty TE1, Luebke A2, Gidal BE3.
https://www.ncbi.nlm.nih.gov/pubmed/25346628



Cannabidivarin(CBDV)suppresses pentylenetetrazole(PTZ)-induced increasesinepilepsy-relatedgene expression
Naoki Amada1,2,3, Yuki Yamasaki1,2,3, Claire M. Williams2 and Benjamin J. Whalley1
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840466/pdf/peerj-01-214.pdf


Report from a Survey of Parents Regarding the Use of Cannabidiol (Medicinal cannabis) in Mexican Children with Refractory Epilepsy.
Aguirre-Velázquez CG1.
https://www.ncbi.nlm.nih.gov/pubmed/28392943



Cannabidiol Treatment for Refractory Seizures in Sturge-Weber Syndrome.
Kaplan EH1, Offermann EA1, Sievers JW2, Comi AM3.
https://www.ncbi.nlm.nih.gov/pubmed/28454984


Could Cannabidiol be a Treatment Option for Intractable Childhood and Adolescent Epilepsy?
Koo CM1, Kang HC2.

Hypnotic and antiepileptic effects of cannabidiol.
Carlini EA, Cunha JM.
https://www.ncbi.nlm.nih.gov/pubmed/7028792









Are Cryptocurrencies the Future of the Cannabis Industry

Are Cryptocurrencies the Future of the Cannabis Industry


The legal cannabis industry and the cryptocurrency industry appear to have a budding relationship, if you’ll excuse the pun.
The two share a lot of common ground. Both operate in legally gray areas, particularly in the United States. They face many of the same challenges from financial, political, and regulatory standpoints. Their user bases could even be said to overlap, as both legal cannabis and cryptocurrency are most popular with younger demographics.

Their shared traits aside, cannabis and cryptocurrency have complementary business models that are likely to bolster one another as adoption – in both – becomes more widespread. Some companies on both sides of the aisle are already taking advantage of this natural synergy. We’re going to present a brief survey of the separate cannabis and crypto business landscapes and point out the important intersections developing between the two.

Crypto’s Challenges


The challenges facing cryptocurrency adoption are all too familiar. Despite operating in the public sphere for the better part of a decade, cryptocurrencies are still viewed as a fringe financial tool by the mainstream media, public, and financial institutions. Part of this is practical. Cryptocurrencies are relatively new, if viewed from the thousand-year history of currency, and they do not yet enjoy day-to-day use anywhere outside of a few tech enclaves in Malta, Puerto Rico, and some major cities in the U.S. and Asia. They are, in a word, unfamiliar.

Few government regulatory agencies know exactly how to approach them, and even fewer businesses trust them as a secure store of value. This is partly due to their current volatility and partly due to their low adoption rate. It ends up being a bit of a vicious cycle. It’s difficult to get merchants to accept crypto because few individuals or financial institutions are willing to handle them. As a result, fewer merchants are willing to accept them, and round and round the issue goes.


Then there are some very real legal issues. It’s not entirely clear whether some, all, or no cryptocurrencies qualify as securities. They are not traditional currencies, as such, and so are not treated or taxed in the same way. And they possess a technological component that sets them apart. They are stored and traded on blockchains, which offer fast, distributed, and transparent transaction chains. These advantages are a bit of a double-edged sword when it comes to regulation, however, as blockchains can transcend financial institutions, businesses, and even national borders.


The Cannabis Hurdle


Let’s just assume, for the moment, that we’re talking about portions of the world where cannabis is entirely legal. That lets us dispense, to use another pun, with all the areas where cannabis enjoys not-quite-official status – no-enforcement zones, decriminalized areas, and so on. So, we’re really talking about states, in particular, where marijuana dispensaries are all aboveboard, legal, and recognized by the U.S. government.


Even with all that official backing, cannabis dispensaries and farms face significant challenges. Few banks want to offer loans or credit to a marijuana-based enterprise due to the newness of the market and the sticky legal issues that arise when states’ rights come into play. Marijuana is still not legal on the federal level, and because banks are required by law to be federally insured, it’s not entirely clear whether they can play on an equal playing field in the marijuana industry.

This is important. It means that’s the billion-dollar, legal marijuana industry (and marijuana is now legal in two-thirds of U.S. states) must operate on a cash-only basis, much like its black-market cousin. This puts it in the same “unbanked” boat as much of the third world.
The Synergies It’s this “unbanked” situation that really creates the potential for crypto and cannabis to come together. Cryptocurrencies have demonstrated, via their blockchain technology, that they present a viable alternative for folks unwilling or unable to secure traditional banking accounts. As originally spelled out by Bitcoin creator Satoshi Nakamoto in his landmark white paper, cryptocurrencies contain within their blockchains all the trust and information needed to bypass third-party intermediaries, like banks, entirely. Value can be stored in a distributed and open way across the blockchain, and it can be transferred without the involvement of a financial or government entity.

It’s been done before, though the comparison is likely to raise eyebrows. The first widespread adoption case for Bitcoin was actually the Silk Road black market, where drugs, guns, and other unsavory items could be bought anonymously and in an (at the time) untraceable fashion with Bitcoin.


This association between cryptocurrencies and drugs might feel uncomfortable, at first, but they both lend each other an air of respectability in the long-run. Marijuana may be federally proscribed, but it is legal at the state level. Cryptocurrencies might get sideways glances from U.S. tax and regulatory officials, but there’s nothing inherently illegal about owning or using a Bitcoin.


Blockchain tech and cannabis seem to go hand in hand in this regard. Cannabis operators can rely on a blockchain tailored for their use as both a store of value and a transaction medium that’s more secure and easier to handle than cash. At the same time, the blockchain gets a ready-made group of adopters to display as a real-world test case. After all, if the blockchain works well for securely tracking and handling cannabis transactions, why wouldn’t it work just as seamlessly in auto, flight, or grocery transactions?


Both industries have a lot to prove, both to the public and to regulators. The blockchain is practically designed for transparent, easily accountable transactions. This gives cannabis operators some safety from government regulators looking to ensure that product isn’t being moved into still-black markets, and it gives would-be cryptocurrencies some credibility in terms of handling large numbers of day-to-day transactions.

Early Adopters

There are several major projects currently working to wed the crypto and cannabis industries. Most of them popped into being during 2014. The five most prominent are PotCoin, CannabisCoin, DopeCoin, HempCoin, and CannaCoin. As of May 2018, none has yet achieved widespread adoption. At the moment, a new cannabis coin is being rolled out called the VapeCoin which will be accepted on one of the biggest cannabis and vape marketplaces. However, they all share the same basic use case – giving marijuana growers, distributors, and associated industries a common medium of exchange and verifiable store of value.
Tellingly, all but CannaCoin boast market caps in the millions of U.S. dollars. PotCoin, the oldest of the bunch, has a market cap of $31 million.

Growing Up Together

Both crypto and cannabis are brand-new industries. The infrastructure for both is almost nonexistent from every possible angle. In fact, neither enjoy completely legal status across the entire United States. Cannabis is currently only legal on a state-by-state basis, while the U.S. Securities and Exchange Commission has a hands-off policy with regards to cryptocurrency exchanges.


The two are likely to grow up together, so to speak. Their shared challenges create opportunities for complementary growth, particularly in the legal and regulatory arenas. Cryptocurrencies give transparency and accountability to marijuana operators. Marijuana operators create a valuable and stable customer base for cryptocurrencies, in addition to injected capital. Both are poised for growth as U.S. demographics lean increasingly left in terms of regulation. Overall, cannabis and crypto present a unique view of the future financial world.

 

References

https://www.investopedia.com/news/top-marijuana-cryptocurrencies/
https://www.entrepreneur.com/article/307979
https://vapertunity.com
https://vapertunitycoin.com/
https://theeliquidboutique.co.uk/

Health Benefits of Cannabidiol (CBD)

Health Benefits of Cannabidiol (CBD)

Cannabidiol (CBD) has been making the buzz for a while now, and you are probably wondering what the buzz is about. Here is a guide about Cannabidiol, its health benefits, mental health benefits, and its overall use.

Cannabidiol, also known as CBD is one of the numerous cannabinoids in cannabis plants. It is a main active constituent directly derived from hemp. The buzz has been on the several benefits of CBD especially on physical and psychological health; it has even been referred to as the miracle cure to several medical conditions. Asides from such immense benefits, it also has an advantage over Delta-9-tetrahydrocannabinol (THC), another main active constituent seen in cannabis plants. Unlike THC which is psychoactive, CBD is nonpsychoactive and does not give the intoxicating or 'high' feeling experienced when ingested. The World Health Organization's Expert Committee on Drug Dependence concludes that 'In humans, CBD exhibits no effects indicative of any abuse or dependence potential,' during a research on Cannabinoids in Cannabis plants.

Studies have revealed that CBD helps to treat and manage certain health conditions as well as to improve certain physiological conditions in the human body. It is known to have anti-cancer properties; hence, it is used in the fight against cancer. It is also known for its analgesic effect and can be used to treat and manage chronic pain in conditions like fibromyalgia. Other benefits of CBD include enhancing bone growth, reducing risks of diabetes, increasing appetite, etc.

When it comes to Mental health, CBD is known to play a major role in the treatment of Epilepsy in Children, especially in alleviating seizures. It is also known to be useful for treating Anxiety, Depression and other stress-related mental disorders. Neurodegenerative disorders and sleep disorders have also been discovered to respond positively to the use of Cannabidiols.

Cannabidiol has been revealed to promote cognitive function, which is seen in the interaction of CBD in the endocannabinoid system as well as the body's central nervous system. Research has also shown that CBD manages sleep patterns, which helps to cure insomnia and navigates triggers that may lead to panic attacks and mood changes.

Cannabidiol has numerous health benefits that cannot be quantified and research is still ongoing to discover more ways it can be used in improving mental health. CBD is also useful in the immune system where it enhances autoimmunity, reduces inflammation and maintains homeostasis within the immune system. CBD can also be used in the treatment and management of some bacterial infections and bone deformations like Rheumatoid arthritis, Osteoarthritis, etc.

Cannabidiol is a safe constituent as it has no known adverse effects and this gives it an edge over other types of treatment options.